SharePoint 2007 Accessibility. Is it possible or practical?

Some days after strugging with code, content, layout and design in MOSS 2007 do you feel you are hitting your head against a wall when you realise how inaccessible (in terms of accessibiity) your site has really become?

You can feel even gloomier when you read articles such as the following:

The More Accessible Mode allows some relief.  Not sure when I’ll get to use these next now, but perhaps these links will be helpful to someone else in the same dilemma: